Vaccine distibution Logistics: Pfizer & BioNTech Experience Early Vaccine Shipping and Distribution Hiccups - by Mark Terry

On Tuesday, the Pfizer-BioNTech vaccine was granted temporary authorization in the UK and dosing will begin next week. The FDA has scheduled an advisory committee meeting for next week, December 8, 9 and 10, for the Pfizer-BioNTech product and potentially could grant approval on December 10, or within a few days afterward. The Moderna’s advisory committee meeting is scheduled for December 17.

The companies, including AstraZeneca-University of Oxford, which is running a close third, as well as the numerous others who have COVID-19 vaccines in development, have astonished skeptics by the speed with which they have developed vaccines that appear to be safe and effective. But now comes an even more daunting challenge—scaling up manufacturing and distribution to deliver the vaccine to populations around the world in a timely and effective manner.

In November, Pfizer and BioNTech had indicated it expected to transport half the COVID-19 vaccine it had originally planned for the year. That didn’t go quite as hoped.

“Scaling up the raw material supply chain took longer than expected,” a company spokeswoman told The Wall Street Journal. “And it’s important to highlight that the outcome of the clinical trial was somewhat later than the initial projection.”

Pfizer-BioNTech had original plans to roll out 100 million vaccines globally by the end of this year, but are now saying 50 million. They still believe they can manufacture more than a billion doses in 2021, enough for about 500 million people.

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EU: Coronavirus -Remdesivir: Commission signs a joint procurement contract with Gilead for the supply of Remdesivir

 The Commission has signed a joint procurement framework contract with the pharmaceutical company Gilead for the supply of up to 500,000 treatment courses of Veklury, the brand name for Remdesivir, and the opportunity to increase supply beyond the 500,000 treatment courses. There are  36 signatories of the Joint Procurement Agreement participating in this joint procurement, including all EU countries, the EEA countries of Norway and Iceland*, the UK, as well as six candidate countries and potential candidates (Albania, the Republic of North Macedonia, Montenegro, Serbia, Kosovo** and Bosnia and Herzegovina). All participating countries can now place their orders to procure Veklury directly. Veklury is at this stage the only medicine with a conditional marketing authorisation in the EU for the treatment of COVID-19 patients needing oxygen supply.

Read more at: Coronavirus: Remdesivir